A clinically important improvement in CNC words was shown in the bimodal condition, with a mean difference of 37.2% (95% CI, 32.0%-42.4%), and in the unilateral (cochlear implant only) condition, with a mean difference of 44.1% (95% CI, 39.0%-49.2%). Mixed-model analysis with estimated marginal means and 95% CIs compared preimplantation baseline performance with 6-month postimplantation performance.
Results Seventy participants (51 men ) with a median age of 74 (range, 65-91) years were included in the analysis. Secondary objectives were QoL metrics in the everyday listening condition before and 6 months after implantation. Main Outcomes and Measures The primary objective was to evaluate speech perception before and 6 months after activation of a new cochlear implant. Hearing aid use in the contralateral ear was required through the 6-month primary end-point interval. Interventions Unilateral implantation with a slim, modiolar cochlear implant device. Data were analyzed from March 25, 2019, to March 31, 2020. Participants were enrolled from February 20, 2017, to May 3, 2018, and follow-up was completed December 21, 2018. Baseline QoL testing was performed after 1 month of optimized bilateral hearing aid use. Participants 65 years or older with postlingual bilateral moderate-to-profound sensorineural hearing loss with aided Consonant-Vowel Nucleus-Consonant (CNC) word scores in quiet of 40% or less in the ear to undergo implantation and 50% or less in the contralateral ear were included in the analysis.
#MOCA NETWORK TRIAL#
Objective To explore the audiometric and holistic effects of cochlear implantation in a group of adults 65 years or older compared with an optimized bilateral hearing aid condition.ĭesign, Setting, and Participants This ad hoc secondary analysis of a prospective, single-subject, repeated-measures nonrandomized clinical trial included 13 cochlear implantation centers across the United States. Moreover, having ineffective binaural hearing increases difficulty understanding speech in noise and leads to a greater degree of social isolation and loneliness and a reduced quality of life (QoL).
Importance Hearing loss, especially moderate to severe forms, has the potential to negatively affect an individual’s physical, social, emotional, and cognitive well-being. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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